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翻訳と辞書　辞書検索 [ 開発暫定版 ] スポンサード リンク White Collar-1 ： ウィキペディア英語版 White Collar-1 White Collar-1 (''wc''-1) is a gene in ''Neurospora crassa'' encoding the protein WC-1 (127 kDa).〔 WC-1 has two separate roles in the cell. First, it is the primary photoreceptor for ''Neurospora'' and the founding member of the class of principle blue light photoreceptors in all of the fungi. Second, it is necessary for regulating circadian rhythms in FRQ. It is a key component of a circadian molecular pathway that regulates many behavioral activities, including conidiation. WC-1 and WC-2, an interacting partner of WC-1, comprise the White Collar Complex (WCC) that is involved in the ''Neurospora ''circadian clock. WCC is a complex of nuclear transcription factor proteins, and contains transcriptional activation domains, PAS domains, and zinc finger DNA-binding domains (GATA). WC-1 and WC-2 heterodimerize through their PAS domains to form the White Collar Complex (WCC). While mainly identified and studied in fungi, members of the White Collar-1 gene family have also been found to be expressed in bovine lymphocytes. == Discovery == The ''Neurospora ''circadian clock was discovered in 1959, when Pittendrigh et al. first described timing patterns in the asexual development of spores. They noticed that in the region of the growing front, mycelia laid down between the late night to early morning formed aerial hyphae, whereas those laid down at other times did not.〔 This aerial growth pattern at subjective circadian times served as tentative support for the presence of circadian oscillators. White Collar-1 was described in the 1960s by geneticists who saw a strain of ''Neurospora'' which the mycelia were albino, but the conidia were normally pigmented. The mutant gene was designated ''white collar (wc),'' for the white coloration of the mycelia below the pigmented conidia on agar slants. The gene ''wc''-1 was classified during the mapping of the chromosomal loci of ''Neurospora crassa (1982 by Perkins et al.). 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「White Collar-1」の詳細全文を読む スポンサード リンク 翻訳と辞書 : 翻訳のためのインターネットリソース Copyright(C) kotoba.ne.jp 1997-2016. All Rights Reserved.